05/22/2026
“When landlords turn the drunken bee / Out of the foxglove’s door, / When butterflies renounce their drams, / I shall but drink the more!” - I taste a liquor never brewed, Emily Dickinson 🪻
Also known as ‘fairy caps’ or ‘witches’ thimbles,’ the foxglove– in addition to housing the drunken bee – caught the attention of Dr. William Withering in 1775. He learned of the plant’s uses from an elderly woman in Shropshire, who “had sometimes made cures after the more regular practitioners had failed.” Specifically, this ‘old lady of Shropshire,’ was stated to have a cure for dropsy (what we now refer to as edema) made of 20 different herbs. Of these, Dr. Withering noted that the active ingredient was foxglove.
Over the course of the following 10 years, he prescribed it often. He often spoke about foxglove and its properties with ‘the poor’ of his town, for whom he would give advice for one hour every day free of charge. He eventually compiled his thoughts into a book “An Account of the Foxglove,” in 1785. Dr. Withering’s goal in his administration of foxglove was for its use as a diuretic, which he claimed the plant was able to do “more generally than any other medicine,” although admitted that it did not work in every patient.
Interestingly, though, his final “inference” about foxglove is the one that would become the most important: “That it has power over the motion of the heart, to a degree yet unobserved in any other medicine.”
He was more right than perhaps he knew. Foxglove, Latin name “digitalis purpurea,” is a cardiac glycoside (a term that means, functionally, that it decreases heart rate while increasing contraction strength). Separated by hundreds of years and miles, today we call the drug derived from foxglove “digoxin,” used for heart failure when other treatments fail.
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