Sikeston Depot Museum & Cultural Center

Sikeston Depot Museum & Cultural Center This museum is FREE. Located at 116 West Malone Avenue in beautiful downtown Sikeston.
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05/20/2026

Please note the Depot has a new phone number: 573-475-7318.

Don Lloyd Wood Carvings May, June & July Wed-Sat 10AM-4PM
05/08/2026

Don Lloyd Wood Carvings
May, June & July
Wed-Sat 10AM-4PM

04/03/2026

Regional High School Art Show
Open House Friday, April 17th 5-7:30pm

02/27/2026
Black History Month @ The Depot
02/03/2026

Black History Month @ The Depot

Come check out The Corner Grocery Store at the Sikeston Depot!
12/02/2025

Come check out The Corner Grocery Store at the Sikeston Depot!

Open House Friday, December 5th, 10AM-5PM.
12/02/2025

Open House Friday, December 5th, 10AM-5PM.

Nov 1, 2025 - Jan 31, 2026
10/28/2025

Nov 1, 2025 - Jan 31, 2026

Wonderful turnout downtown this morning!
08/02/2025

Wonderful turnout downtown this morning!

07/31/2025

The Sikeston Depot Museum presents:

Tiffany Brantley, local artist from Charleston, MO.

August through October 2025

Wednesday thru Saturday 10AM to 4PM

Address

116 W Malone Avenue
Sikeston, MO
63801

Opening Hours

Wednesday 10am - 4pm
Thursday 10am - 4pm
Friday 10am - 4pm
Saturday 10am - 4pm

Telephone

(573) 481-9967

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